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Postgraduate Education Corner |

Dyspnea in a 43-Year-Old Woman With Polycystic Kidney Disease

Howard Y. Li, MD*; Gregory P. Cosgrove, MD, FCCP; Jeffrey J. Swigris, DO, MS
Author and Funding Information

*From the Department of Medicine (Dr. Li), Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado at Denver and Health Sciences Center, Denver, CO; and Division of Pulmonary Medicine (Drs. Cosgrove and Swigris), Interstitial Lung Disease Program, National Jewish Medical and Research Center, Denver, CO.

Correspondence to: Howard Y. Li, MD, University of Colorado at Denver and Health Sciences Center, 4200 East Ninth Ave, Box C-272, Denver, CO 80262; e-mail: Howard.Li@uchsc.edu

*Adapted with permission from Cosgrove et al.1

*Adapted from Hyman and Whittemore.9

†When both LAM and renal angiomyolipomas are present, other features of TSC should be present before a definitive diagnosis is assigned.

‡Histologic confirmation is suggested.

The authors have no conflicts of interest to disclose.

Reproduction of this article is prohibited without written permission from the American College of Chest Physicians (www.chestjournal.org/misc/reprints.shtml).


The authors have no conflicts of interest to disclose.

The authors have no conflicts of interest to disclose.

Reproduction of this article is prohibited without written permission from the American College of Chest Physicians (www.chestjournal.org/misc/reprints.shtml).

Reproduction of this article is prohibited without written permission from the American College of Chest Physicians (www.chestjournal.org/misc/reprints.shtml).


Chest. 2009;135(1):238-243. doi:10.1378/chest.08-1223
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Extract

A 43-year-old Vietnamese-American woman was referred for evaluation of dyspnea. Six months prior to presentation, left-sided chest pain radiating to her shoulder had developed, and she also noted nonproductive cough and decreased exercise tolerance. These symptoms resolved spontaneously after 10 days, and she returned to her usual state of good health. Within a few weeks began the insidious onset of progressive exertion-related dyspnea. She denied fevers, night sweats, weight loss, cough, sputum production, hemoptysis, wheezing, or recurrent chest pain. She was seen by her primary care physician who started her on loratadine, 10 mg/d, and albuterol by metered-dose inhaler. When her symptoms failed to improve, she was referred to our institution.

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