PURPOSE: The purpose of this study was to get an overview of wood workers sensitization in different kinds of wood.
METHODS: We have examined 59 workers,aged 47-53 years,non-smokers,suspected, according their medical history from general practitioners, to have suffered from wood-dust asthma.Serological tests for several kinds of wood and skin prick tests were performed.Data describing occupational lung disease and allergical diagnostics were used.
RESULTS: In all workers the skin prick tests were negative.In 7 workers IgE antibodies against mahagoni,abachi and limba (kinds of wood) were found.These results were confirmed by IgE-inhibition tests and a cross-reactivity of the IgE-antibodies against limba and abachi allergens was positive detectable.In 3 of the 7 positive workers an inhalation challenge test with limba and abachi extracts was performed (voluntarily)and they developed rhinitis as a asthmatic reaction.
CONCLUSIONS: Our results revealed that in most cases of suspected clinical wood dust asthma a IgE mediated hypersensitivity was not proven.
CLINICAL IMPLICATIONS: There is a need for a wood extraction preparation , sui-table for skin prick tests and IgE analysis.
DISCLOSURE: The following authors have nothing to disclose: Nikolaos Tatsis, Fotini Babatsikou, Dimitrios Korogiannos, Eugenios Metaxas, Marios Kougias, George Tatsis
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