PURPOSE: The purpose of this study was to describe patient outcomes, and factors in successful weaning
METHODS: This study included 100 patients (45 males & 55 females) with mean age of 57.8 years, with respiratory failure due to different pulmonary diseases were admitted to RICU for mechanical ventilation between October 2008 to October 2010 .
RESULTS: A total of 100 patients on MV were included in the study. Ninety percent of patients were successfully weaned. Unsuccessfully weaned patients had higher rapid shallow breathing index (RSBI), higher PaCO2, lower static complaince and lower serum albumin. There was significant correlation between duration of MV and serum albumin (r=-o.99, P<0.01) , K (r=-o.48, P<0.01) RBCs count(r=-o.5, P<0.007), static compliance (r=-o.6, P<0.001) and RSBI(r=o.62, P<0.001). There was insignificant relation between serum k &Na, RBCs & WBCs counts, PH, PaO2, O2saturation, age, sex , body temperature, Respiratory rate and weaning outcome. Factors found to be associated with Unsuccessful weaning were serum albumin (p<0.02), PCO2 (P<0.01), static compliance (P<0.001), RSBI (p<0.01), length of ICU stay & diagnosis of cases(p<0.03).
CONCLUSIONS: weaning from mechanical ventilation is a complicated process depends on multiple factors. Factors associated with unsuccessful weaning included longer duration of ICU stay and lower static compliance & serum albumin level and higher RSBI &PaCO2 level.
CLINICAL IMPLICATIONS: For adult patients on mechanical ventilation, successful weaning has been attributed to various factors
DISCLOSURE: The following authors have nothing to disclose: Hamdy Mahmoud
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