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Commentary |

The Fontana Paradoxical Reflex?Fontana2019s Paradoxical Reflex?

Federico Lavorini, MD; Giovanni Fontana, MD; Elisa Chellini, MD; Chiara Magni, MD; Massimo Pistolesi, MD; John Widdicombe, DM
Author and Funding Information

From the Department of Internal Medicine (Drs Lavorini, Fontana, Chellini, Magni, and Pistolesi), University of Florence, Italy, and University of London (Dr Widdicombe), London, England.

Correspondence to: Giovanni A. Fontana, MD, Department of Internal Medicine, Immunoallergology, Respiratory Medicine and Cell Therapy, Viale GB Morgagni, 85, 50134 Firenze, Italy; e-mail: giovanni.fontana@unifi.it


Died August 26, 2011.

For related article see page 690

Reproduction of this article is prohibited without written permission from the American College of Chest Physicians (http://www.chestpubs.org/site/misc/reprints.xhtml).


© 2011 American College of Chest Physicians


Chest. 2011;140(3):586-588. doi:10.1378/chest.11-0262
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This commentary describes the “deflation cough” caused by deep lung deflations. Deflation cough is a paradoxical reflex similar to that described by Henry Head in 1889 for lung inflations that probably is mediated by the same sensors and afferent fibers in the lungs and activated by gastroesophageal reflux. We discuss how this reflex must be self-limiting, the general role of paradoxical reflexes in the body, and the possible clinical significance of deflation cough.


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reflex

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