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Postgraduate Education Corner: CONTEMPORARY REVIEWS IN CRITICAL CARE MEDICINE |

Toxicology in the ICUToxicology in the ICU, Part 1: Part 1: General Overview and Approach to Treatment

Michael Levine, MD; Daniel E. Brooks, MD; Carrie A. Truitt, MD; Brian J. Wolk, MD; Edward W. Boyer, MD, PhD; Anne-Michelle Ruha, MD
Author and Funding Information

From the Department of Medical Toxicology (Drs Levine, Brooks, Truitt, and Ruha), Banner Good Samaritan Medical Center, Phoenix, AZ; and the Division of Medical Toxicology (Drs Wolk and Boyer), Department of Emergency Medicine, University of Massachusetts, Worcester, MA.

Correspondence to: Michael Levine, MD, Department of Medical Toxicology, Banner Good Samaritan Medical Center, 925 E McDowell Rd, 2nd Floor, Phoenix, AZ 85006; e-mail: michael.levine@bannerhealth.com


Reproduction of this article is prohibited without written permission from the American College of Chest Physicians (http://www.chestpubs.org/site/misc/reprints.xhtml).


© 2011 American College of Chest Physicians


Chest. 2011;140(3):795-806. doi:10.1378/chest.10-2548
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Poisonings, adverse drug effects, and envenomations continue to be commonly encountered. Patients often present critically ill and warrant ICU admission. Many other patients who are initially stable have the potential for rapid deterioration and require continuous cardiopulmonary and neurologic monitoring. Given the potential for rapid deterioration, and because patients need continuous monitoring, ICU admission is frequently required. This article is the first of a three-part series to be published in CHEST; it discusses general management, laboratory tests, enhanced elimination, and emerging therapies. The second article will address the management of specific overdoses; the last will cover plants, mushrooms, envenomations, and heavy metals.

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