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Editorials: POINT/COUNTERPOINT EDITORIALS |

Rebuttal From Dr Peters

Stephen P. Peters, MD, PhD, FCCP
Author and Funding Information

From the Center for Genomics and Personalized Medicine Research, Wake Forest Health Sciences.

Correspondence to: Stephen P. Peters, MD, PhD, FCCP, Wake Forest University Health Sciences, Center for Genomics and Personalized Medicine Research, Medical Center Blvd, Winston-Salem, NC 27157; e-mail: sppeters@wfubmc.edu


Financial/nonfinancial disclosures: The author has reported to CHEST the following conflicts of interest: Dr Peters has been a member of the Wake Forest Clinical Trials Group, which has performed clinical trials for Ception/Cephalon, GlaxoSmithKline, and Medimmune examining the effect of anti-IL5 therapies in patients with severe asthma.

Reproduction of this article is prohibited without written permission from the American College of Chest Physicians (http://www.chestpubs.org/site/misc/reprints.xhtml).


© 2011 American College of Chest Physicians


Chest. 2011;139(6):1277-1278. doi:10.1378/chest.11-0628
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Extract

Drs Hargreave and Nair have both made extensive contributions to our understanding of airway inflammation and eosinophils in the pathogenesis and treatment of asthma and have provided a reasoned rationale for using sputum eosinophilia as an aide in managing severe asthma.1 However, I remain unconvinced by their arguments for two reasons, one practical and one conceptual.

1HargreaveFENairPPoint: is measuring sputum eosinophils useful in the management of severe asthma? YesChest20111396127012732PetskyHLCatesCJLassersonTJA systematic review and meta-analysis: tailoring asthma treatment on eosinophilic markers (exhaled nitric oxide or sputum eosinophils) [published online ahead of print October 11, 2010]Thoraxdoi:10.1136/thx.2010.1355743DormanSBussoliMRitzSAlcohol fixation of induced sputum samples for applications in rural communitiesCan Respir J2010173115121

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