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Postgraduate Education Corner: PULMONARY AND CRITICAL CARE PEARLS |

A 47-Year-Old Woman With Progressive Dyspnea and Hypoxemia After Lung Transplantation

Shambhu Aryal, MD; Rayan Ihle, MD; Don Hayes, Jr, MD, FCCP; Ketan P. Buch, MD, FCCP
Author and Funding Information

From the Division of Pulmonary and Critical Care Medicine, University of Kentucky, Lexington, KY.

Correspondence to: Shambhu Aryal, MD, Division of Pulmonary and Critical Care Medicine, University of Kentucky, 740 S Limestone St, Ste L543, Lexington, KY 40536; e-mail: sar222@uky.edu


Reproduction of this article is prohibited without written permission from the American College of Chest Physicians (http://www.chestpubs.org/site/misc/reprints.xhtml).


© 2011 American College of Chest Physicians


Chest. 2011;139(6):1532-1535. doi:10.1378/chest.10-2856
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Extract

A 47-year-old white woman with a history of left-single lung transplant for idiopathic pulmonary fibrosis two years prior was admitted to the hospital with progressive dyspnea. Her postoperative course was complicated by repeated episodes of resistant acute rejection associated with aspiration. She also developed early-onset bronchiolitis obliterans syndrome (BOS) with bronchiectasis. At the time of admission, the patient’s symptoms were ascribed to worsening BOS. She had intermittent fevers, easy fatigability, and malaise, but denied having worsening edema, palpitations, skin changes, muscle weakness, chest pain, or arthritic symptoms.

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