Our findings show that ARDS survivors have a poorer quality of life at 6 months compared with an age-matched and sex-matched reference population from the same geographic area, which is mainly because of alterations in the dimensions focusing on the more physical components. Furthermore, a higher degree of social isolation has been observed in ARDS survivors. It may be a consequence, at least in part, of this alteration in physical domains. On the other hand, there was a robust relationship between the overall HRQL encountered at 1 month and at 6 months after ARDS, which indicates that identification of patients who will have a poor long-term quality of life is possible at an early time point. The decrease in HRQL is consistent with prior reports.11,15‐22 In fact, some studies have reported a reduction in HRQL after ARDS that was similar to,23 or even worse18 than, that seen in patients with other chronic diseases. Indeed, a meta-analysis of 557 patients grouped in 13 different cohorts24 reported three important conclusions. First, studies using the 36-Item Short Form Health Survey (SF-36)11,13,17,19 showed similar differences in HRQL, suggesting that the deterioration experienced by survivors was due to common factors. Second, the improvements seen in each dimension of the HRQL questionnaire were independent, and moreover, depended on the time at which they were measured. Lastly, survivors of ARDS presented a poorer HRQL compared with the age-matched and sex-matched reference population. Although most studies used SF-36 to evaluate HRQL, it is important to notice that significant alterations in HRQL were also observed when NHP was used. However, the characteristics of the test used may have influenced the results observed. Compared with SF-36, NHP may be less sensitive in detecting milder degrees of disease. However, NHP gives more coverage to emotional reaction, pain, and physical mobility. Moreover, unlike SF-36, NHP includes problems of sleep disturbance. Despite these differences, when a large cohort of patients with COPD was analyzed, both instruments had a similar ability to discriminate among different levels of respiratory impairment.25 Nevertheless, to our knowledge, no data about comparisons of both tests in ARDS patients have been collected.