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Postgraduate Education Corner: PULMONARY AND CRITICAL CARE PEARLS |

A 62-Year-Old Male Heart Transplant Recipient With Progressive Hypoxia

Jason A. Stamm, MD; M. Hong Nguyen, MD; Sara E. Monaco, MD; Yoshiya Toyoda, MD, PhD; Arthur J. Boujoukos, MD
Author and Funding Information

From the Division of Pulmonary and Critical Care Medicine (Dr Stamm) and the Division of Infectious Disease (Dr Nguyen), Department of Medicine; the Department of Pathology (Dr Monaco); the Department of Cardiothoracic Surgery (Dr Toyoda); and the Department of Critical Care Medicine (Dr Boujoukos), University of Pittsburgh Medical Center, Pittsburgh PA.

Correspondence to: Jason A. Stamm, MD, Division of Pulmonary and Critical Care Medicine, NW 628, Montefiore University Hospital, 3459 Fifth Ave, Pittsburgh, PA 15213; e-mail: stammja@upmc.edu


Reproduction of this article is prohibited without written permission from the American College of Chest Physicians (http://www.chestpubs.org/site/misc/reprints.xhtml).


© 2011 American College of Chest Physicians


Chest. 2011;139(4):954-957. doi:10.1378/chest.10-2414
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A 62-year-old man with a history of ischemic cardiomyopathy underwent orthotopic heart transplantation. Before transplantation, he completed three monthly cycles of plasmapheresis, with administration of IV immunoglobulin (Ig) to reduce the level of preexisting human leukocyte antigen antibodies. On the day of transplant, he was determined to be IgG seropositive for cytomegalovirus and Toxoplasma gondii. The patient was induced with alemtuzumab and received tacrolimus and mycophenolate mofetil for immunosuppression. He recovered uneventfully in the early posttransplant course.

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