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Editorials |

The Pulmonary Arteries, Idiopathic Pulmonary Fibrosis, and Lung Transplantation: Deciphering the Connection

Chee M. Chan, MD, MPH; Andrew F. Shorr, MD, MPH, FCCP
Author and Funding Information

From Pulmonary and Critical Care Medicine, Washington Hospital Center.

Correspondence to: Chee M. Chan, MD, MPH, Pulmonary and Critical Care Medicine, Washington Hospital Center, 110 Irving St NW, #2B-39, Washington, DC 20010; e-mail: chee262@hotmail.com


Financial/nonfinancial disclosures: The authors have reported to CHEST that no potential conflicts of interest exist with any companies/organizations whose products or services may be discussed in this article.

Reproduction of this article is prohibited without written permission from the American College of Chest Physicians (http://www.chestpubs.org/site/misc/reprints.xhtml).


© 2011 American College of Chest Physicians


Chest. 2011;139(4):741-743. doi:10.1378/chest.10-2400
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Extract

Over the past decade, our understanding of idiopathic pulmonary fibrosis (IPF) has improved substantially. In addition to newer pathologic classification schemes and a greater appreciation of the variable natural history of this syndrome, researchers have developed improved tools for risk stratification and prognostication.1-3 We also have seen the publication of large, multicenter randomized trials for the treatment of IPF along with the creation of a multi-institutional, National Heart, Lung, and Blood Institute-funded research group.4,5 Unfortunately, despite all of this progress, IPF remains almost uniformly a fatal disease. The only intervention that appears associated with improved survival remains lung transplantation.6

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