Electromagnetic navigation, as described in the article by Seijo and colleagues5 in this issue of CHEST (see page 1316), attempts to improve the diagnostic yield of flexible bronchoscopy in such peripheral lung lesions. This system functions like a global positioning system within the patient’s thorax, with a steerable probe that aims to enable the operator to navigate to lesions in the lung parenchyma beyond what is endoscopically visible. It remains but one of a number of emerging technologies in this field, and most literature to date consists of uncontrolled retrospective case series. Each step in the process of bronchoscopic lung biopsy has been targeted by these innovations: (1) preprocedure planning (eg, multiplanar CT scan reconstruction6), (2) endoscopic navigation (eg, electromagnetic navigation, virtual bronchoscopic navigation7), and (3) confirmation of localization (eg, radial probe endobronchial ultrasound,8 CT scan fluoroscopy9). All of these modalities are attempting to obviate the need for transthoracic needle biopsies, which carry a well-documented, significant risk of pneumothoraces.10 This risk of pneumothorax is further magnified in patients with obstructive spirometry, when multiple biopsy punctures are needed, and when the transthoracic needle-path length exceeds 40 mm.9 However, new bronchoscopic technology comes with incumbent high costs and steep learning curves. Therefore, it is critical to weed out modalities with only a marginal increment in diagnostic yield and select the right procedure for the right patients.