PURPOSE: The prevalence of Obesity is on the rise. Obese patients often complain of dyspnea and seek medical attention for effort intolerance. PFTs are ordered to help explain the cause of dyspnea.Physicians need be aware of PFT abnormalities due to Obesity so as to avoid errors in diagnosis and misguided therapy. The purpose of the study is to characterize prevalence and severity of PFT abnormalities in obesity.
METHODS: Retrospective review of PFT records of all obese patients (BMI>30) that were referred to PFT Laboratory for evaluation of dyspnea or preoperative PFT during the time period between 1/09 to12/09 were reviewed. The following information were extracted from computerized PFT database:.Demographic data, smoking status, TLC, FRC, ERV, VC were expressed as % of NHANES-II reference values. All PFT ( TLC/FRC/ERV/VC) data were categorized as Normal >80% Predicted, Mild restriction 65-79%, moderate, 50-64%, and severe < 49% .
RESULTS: There were 131 patients, M-41, F-90, median age 53 Years, range (20-79 ). Smokers 33.6% , Non-smokers 66.4% ,African American 61%,Hispanic 27.4%,Caucasians 9.1%, Others 2.5%, BMI median, range 34 (30.-67.3 ). 67 patients were classified as obese ( BMI 30-35), 28 with Moderate obesity36-40) and 36 with Morbid obesity (> 41). Sub group analysis failed to reveal a linear correlation between prevalence and Severity of PFT abnormalities and BMI.
CONCLUSION: PFT abnormalities are common in Obesity and help explain effort intolerance. Our study failed to show a linear correlation between severity of obesity (BMI) and prevalence and severity PFT abnormalities.Further studies are needed to correlate PFT abnormalities with Height Waist Index.
CLINICAL IMPLICATIONS: Physicians need be aware of PFT abnormalities due to Obesity so as to avoid errors in diagnosis and misguided therapy.
DISCLOSURE: Sasikanth Nallagatla, No Financial Disclosure Information; No Product/Research Disclosure Information