Poster Presentations: Wednesday, November 3, 2010 |

Vibration Response Imaging as a New Tool for Outcome Assessment of Interventional Bronchoscopy: An International Multicenter Validation Study FREE TO VIEW

Heinrich D. Becker; Teruomi Miyazawa, MD; Ali Musani, MD; Herve Duteau, MD; Mohman Wahidi, MD; Merav Gat, MSc
Author and Funding Information

Dept. Interdisciplinary Endoscopy at Thoraxklinik at Heidelberg University, Heidelberg, Germany

Chest. 2010;138(4_MeetingAbstracts):434A. doi:10.1378/chest.10923
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PURPOSE: Bronchoscopic interventions for central airway obstruction are increasing. However, benefit of interventions frequently cannot be objectified.We compared findings from a multi-center study to a preliminary report on mapping of breath sounds providing objective qualitative and quantitative information regarding central airway obstruction and outcome.

METHODS: Vibration response images (VRI) from 86 patients suspected of central airway stenosis (CAO) were evaluated by two blinded raters. Qualitative and quantitative dynamic and static features were documented for normal or abnormal and change after intervention. Also stenosis location was evaluated compared to bronchoscopic findings. Treatment outcome (improved vs. not improved) was analyzed comparing baseline and follow-up images in 94 interventions. VRI was compared to standards (dyspnea score, pulmonary function testing, x-ray/CT and bronchoscopy [gold standard]). Results were compared to the pilot study.

RESULTS: VRI accuracy locating CAO compared to bronchoscopy was 71%. Correct detection of the affected side was 82%. VRI accuracy after intervention was 88% in defining outcome. The findings were the same as in the pilot study.

CONCLUSION: Obstruction location and procedure outcome were reliably identified. VRI proved to be equivalent to standard tests for localization of CAO.

CLINICAL IMPLICATIONS: VRI may replace pulmonary function testing or imaging procedures when such tests cannot be performed or are not readily available at time of intervention.

DISCLOSURE: Heinrich Becker, Grant monies (from industry related sources) The study was supported by DeepBreeze Ltd., Or Akiva, Israel by providing the VRI devices and financially for logistics.; Consultant fee, speaker bureau, advisory committee, etc. HDB received finacial support for presentation at meetings; No Product/Research Disclosure Information

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