PURPOSE: Asthma is a disease with increasing global significance. Traditionally, physiological indices like FEV1,FVC, and PEF have been the common means of monitoring the disease. These however have not been found to adequately represent the patient’s perception of the disease. The health -related quality of life encapsulate a patient’s whole life experience and thus constitute an important way of assessing the impact of a disease on their day to day activities.
METHODS: Fifty Asthmatics were recruited consecutively from the respiratory unit of Obafemi Awolowo University Teaching Hospital ,Ile-Ife, Nigeria. They all had pulmonary function testing and parameters like the FEV1 ,FVC, FEV1/FVC and PEF. Their health-related quality of life was assessed using the St. Georges’ Respiratory Questionnaire(SGRQ) and they all had the six-minute walk test. Their dyspnea ratings was assessed using the Borg and Visual Analogue scale before and after the six-minute walk.
RESULTS: The Mean age of the subjects were 37.4±18.2yrs, FEVI 1.84±0.56L, FVC 2.35±0.62L, FEV1/FVC 78±15 and PEF 296±92L/min. The mean SGRQ scores were 44.2±23.1, 37.7±23.4, 26.9±15.7,33.1±16.3 in the Symptom, Activity ,Impact and Total domains respectively. No significant relationship was found between the SGRQ variables and the lung function parameters .There was however a significant negative correlation between the distance walked in Six minute and the SGRQ scores .The BMI was also noticed to correlate positively with the impact domain of the SGRQ scores; r=0.307 ,p 0.03.
CONCLUSION: The use of health-related quality of life instruments like the SGRQ is a simple, accessible and reproducible means of assessing Asthma. The health-related quality of life does not seem to correlate with the spirometric indices as it appears they are assessing different aspect of the disease.
CLINICAL IMPLICATIONS: It is important that the Health-Related Quality of Life measures complement other physiological means of assessing the Asthmatics.
DISCLOSURE: Bamidele Adeniyi, No Financial Disclosure Information; No Product/Research Disclosure Information