PURPOSE: To compare the diagnosis rate and time to diagnosis of nontuberculous mycobacterial (NTM) lung disease by 1997 American Thoracic Society (ATS) guideline and by 2007 ATS/Infectious Disease Society of America (IDSA) guideline.
METHODS: The medical records of patients who had excreted NTM at least one time at St Carollo Hospital between January 2005 and December 2008 were reviewed. New 2007 ATS/IDSA guideline was applied to these patients. The difference of the rate of the diagnosis and of the time to diagnosis were compared.
RESULTS: Between 2005-2008, 168 patients were revealed to have positive NTM culture from their respiratory specimen at least one time. 19 of 168 patients(11.3%) were diagnosed with NTM lung disease by 1997 ATS diagnostic guideline. When new ATS/IDSA guideline was applied to 168 patients, 3 patients were newly diagnosed with NTM lung disease. The diagnosis rate was changed from 11.3% to 13.1%(p=0.483). The time to diagnosis of 1997 ATS guideline and new ATS/IDSA guideline were 45.6±52.5 days and 35.7±38.1 days, respectively(p=0.002).
CONCLUSION: By using new ATS/IDSA guideline, we can shorten the time to diagnose the NTM lung disease. However, more patients were diagnosed with NTM lung disease when new ATS/IDSA guideline used.
CLINICAL IMPLICATIONS: New ATS/IDSA guideline is useful to shorten the time to diagnose the NTM lung disease.
DISCLOSURE: Dongryeol Chae, No Financial Disclosure Information; No Product/Research Disclosure Information