PURPOSE: Describe the clinical features of Influenza A (H1N1) patients hospitalized in Dr. Soetomo General Hospital, Surabaya, Indonesia during the peak 2009 flu pandemy.
METHODS: Review of the medical records of all confirmed Influenza A (H1N1) patients admitted to the hospital.
RESULTS: Among the 133 patients (68 males and 65 females), most were belong to 11-20 years age group (57, 43.86%), followed subsequently by 0-5 years (24, 18.05%), 21-30 years (15, 11.27%), 31-40 years (15, 11.27%), 6-10 years (8, 6.02%), 41-50 years (6, 4.51%), 50-59 years (4, 3.01%), and > 60 years (4, 3.01%) age group. Only 61% of patients had a known source infection contacts. The most prevalent clinical symptom was fever (98.86%) followed by rhinorrhoe (65.90%), dry cough (63.63%), muscular pain (35.23%), sore throat (29.54%), headache (28.41%), sputum production (26.14%), nausea (20.45%) and vomiting (17.04%) respectively. Laboratory assessment showed 8.27% with anemia, 19.55% with leucositosis, and 15.04% with thrombocytopenia. Chest X-ray showed 30.07% of patients with pneumonia. Diagnosis of Influenza A (H1N1) was confirmed by a positive RT-PCR. Most patients (107, 80.45%) did not have any comorbidity, while 2 with chronic pulmonary disease, 1 with diabetes mellitus, 5 with cardiovascular disease, 4 with advanced age, 3 with malnutrition, 4 with congenital heart anomaly, and 7 with hematologic disease or malignancy. None of them were pregnant. One hundred and twenty six patient were successfully recovered from the illness, while the other 7 (5.26%) had died despite all treatment effort, mostly due to sepsis and/or respiratory failure.
CONCLUSION: During the peak 2009 flu pandemy in Indonesia, our hospital received 133 influenza A (H1N1) patients. Most of them were in the 11-20 years age group. Only 61% had a known source of infection. Most patients (80.45%) did not have any comorbity. With our current standard of care we successfully recovered most of the patients, with 5.26% mortality.
CLINICAL IMPLICATIONS: We still need to improve our refferal system and provide special well equipped intensive care room to reduce the mortality rate.
DISCLOSURE: Laksmi Wulandari, No Financial Disclosure Information; No Product/Research Disclosure Information