PURPOSE: this study aims to describe the epidemiologic and clinical criteria and disease burden among H1N1 RT-PCR-Positive and RT-PCR-negative pneumonic patients during 2009-2010 pandemic in Mansoura University Hospitals, Egypt.
METHODS: A retrospective cohort study was conducted for 43 adult pneumonic patients admitted to chest department isolation unit during 2009-2010 H1N1 pandemic with community acquired pneumonia. Out of them 20 patients were confirmed to be H1N1 positive using RT-PCR technique and 23 negative RT-PCR pneumonic patients. Their demographic clinical, laboratory and radiological data were collected and analyzed using SPSS version 10.
RESULTS: H1N1 pneumonic patients group were more significantly presented with sore throat (P=0.005), dyspnea (P=0.002) and GIT complaints (vomiting and diarrhea P=0.02) compared to H1N1 negative group. Also, complications were significantly higher (P=0.01) in H1N1 confirmed pneumonic group than non confirmed pneumonic group. However, no significant differences were found between both groups regarding length of hospital stay, ICU admission and mortality.
CONCLUSION: Sore throat, dyspnea and presence of GIT complaints increase the suspicious of H1N1 positivity in pneumonia during H1N1 pandemic. Also, H1N1 did not worse the burden of pneumonia.
CLINICAL IMPLICATIONS: To increase suspicious of diagnosis H1N1 pneumonia during pandemic. Illuminate the picture of burden and decrease panic from H1N1 infection.
DISCLOSURE: magda Ahmad, No Financial Disclosure Information; No Product/Research Disclosure Information