PURPOSE: To determine whether use of statins in an outpatient cardiology practice affects the long-term incidence of myocardial infarction (MI), percutaneous coronary intervention (PCI), and coronary artery bypass graft surgery (CABGS).
METHODS: Chart reviews were performed in 305 patients who were not treated with statins during the first year of being seen in an outpatient cardiology practice but who were subsequently treated with statins. The 305 patients included 217 men and 88 women, mean age 74 years. Based on the starting date of statin usage, the long-term clinical outcomes of MI, PCI, and CABGS were calculated and compared. Customized computer programming was written to analyze the data. Paired two-sample t-tests were used to determine statistical significance.
RESULTS: The mean follow-up was 66 months before statin usage and 66 months after statin usage (p not significant). MI was present in 31 of 305 patients (10%) before statin usage, and new MI occurred in 13 of 305 patients (4%) after statin usage (p< 0.01). PCI had been performed in 66 of 305 patients (22%) before statin usage and was performed in 41 of 305 patients (13%)after statin usage (p< 0.01). CABGS had been performed in 56 of 305 patients (18%) before statin usage and was performed in 20 of 305 patients (7%) after statin usage (p< 0.001).
CONCLUSION: Statin usage in an outpatient cardiology practice significantly reduces the incidence of new MI, PCI, and CABGS.
CLINICAL IMPLICATIONS: Statin usage in an outpatient cardiology practice significantly reduces the incidence of new MI, PCI, and CABGS.
DISCLOSURE: Hoang Lai, No Financial Disclosure Information; No Product/Research Disclosure Information