PURPOSE: To characterize the role of gender on the age, smoking, histological type, clinical manifestation, staging status and treatment in men and women patients with non-small cell lung cancer (NSCLC).
METHODS: Patients’ data during recent years in a general hospital was collected and retrospectively reviewed. Disparities and variations between men and women were analyzed. Student Test and Pearson’ χ2 test were used for statistical analysis.
RESULTS: Of 921 patients with NSCLC, 647 patients (70.2%) were men and 274 patients (29.8%) were women. Women developed the disease at an earlier age than men(57.9 years vs 60.9 years, P< 0.01).In particular , men with adenocarcinoma were older than those with adenocarcinoma(59.8 years vs 57.9 years, P=0.041).The proportion of Squamous cell carcinoma in men was higher than women (39.6% vs 7.7%, P< 0.01), but the proportion of adenocarcinoma in men was lower (55.2% vs 88.7%, P< 0.01).In all types of NSCLC, men smoked more intensively than women (Squamous cell carcinoma 86.3%:9.5%, P< 0.01,adenocarcinoma 68.1%:3.7% , P< 0.01,other types of NSCLC 75.5%:0, P< 0.01). Men patients suffered from hemoptysis more frequently than women patients (33% vs 19 %, P=0.024).
CONCLUSION: NSCLC was more frequently in men than in women. Women developed the disease at an earlier age than men. In particular, men with adenocarcinoma were older than womene with adenocarcinoma. Higher proportion of squamous cell carcinoma but less adenocarcinoma was observed in men than in women. In all types of NSCLC, men smoked more intensively than women.
CLINICAL IMPLICATIONS: this present that lung cancer patients’ some demographics changment.
DISCLOSURE: Guifang Wang, No Financial Disclosure Information; No Product/Research Disclosure Information