PURPOSE: To study whether the clinico-pothologic characteristics of young lung cancer patients ≤40 years of age differ from those patients >40 years of age.
METHODS: Retrospective analysis was carried out to compare the clinico-pathologic features of 218 young patients (young group) with those of 944 older ones (elderly group) collected from the same period of time.
RESULTS: Young group, when compared with the older group, had more female (39%:27%, P<0.001), different constitution of pathological types (P<0.001) characterized with more adenocarcinoma (51%), more advanced-stage disease (76%:48%, P<0.001) and less patients underwent surgery (26.6%, P<0.001). Cough is the most common presentation (73.9%). Other symptoms like chest pain, breathlessness, loss of weight and haemoptysis are not common. Combined-modality therapy was not common used (20.2%) in the young group.
CONCLUSION: Younger patients with lung cancer present difference in clinico-pathologic features from the older ones. The definition-"the younger type of lung cancer" should be spread to raise the attentions.
CLINICAL IMPLICATIONS: this can present the new character of lung cancer of younger pateits.
DISCLOSURE: Guifang Wang, No Financial Disclosure Information; No Product/Research Disclosure Information