PURPOSE: Tuberculosis (TB ) is an important disease with significant morbidity and mortality worldwide. Nigeria is the 4th burden with the disease worldwide and there is inadequate documented information about the quality of life of those affected with the disease. This study was conducted to determine the effect of socio-demographic and economic factors on the health related quality of life of patients with tuberculosis as well as to determine the aspects of quality of life that is mostly affected by tuberculosis.
METHODS: This was a descriptive cross-sectional study carried out at the chest clinic of Lagos State University Teaching Hospital Ikeja. Non probability sampling method was used and 260 consecutive patients with TB on anti TB medications who consented were recruited into the study between June and September 2009.Information was obtained with an interview based questionnaire which sought information on the socio-demographic and economic characteristics.The WHOQOL-BREF questionnaires were used to collect information on quality of life.This was carried out with SPSS statistical software version 15. Mean for each domain score were calculated and categorized. Categorical variables were compared using the chi square while various means were compared using the independent t test.The level of statistical significance was taken as P< 0.05.
RESULTS: The mean age of the patients was 36.7± 12.6years .There were more males than female with ratio 2.7:1. Gender had no significant effect on physical health and environmental domain of the patients. Males scored significantly lower scores in the Psychological and social relationships domains compared with females.Older patients had lower scores in all domains except the environment that was not significantly affected. There was a significant association between income levels, educational levels and the quality of life.
CONCLUSION: Several factors which include age, gender, marital status, income as well as educational levels, influence the quality of life of patients with tuberculosis.
CLINICAL IMPLICATIONS: Addressing the identified factors as part of treatment in patients with TB may lead to improvement in outcome of treatment.
DISCLOSURE: Olayinka Adeyeye, No Financial Disclosure Information; No Product/Research Disclosure Information