Poster Presentations: Wednesday, November 3, 2010 |

Validity and Reliability of a Single-Item Measure of Quality of Life Scale for Patients With Cystic Fibrosis FREE TO VIEW

Abebaw M. Yohannes, PhD; Thomas Willgoss; Mary Dodd; Francis Fatoye; Kevin Webb, PhD
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Manchestr Metropolitan University, Manchester, United Kingdom

Chest. 2010;138(4_MeetingAbstracts):507A. doi:10.1378/chest.10254
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PURPOSE: There are validated health related quality of life scales for patients with cystic fibrosis. They are lengthy, burdensome to complete but appropriate for research purposes. However, their uses in clinical setting are not fully known. We aimed to assess the validity and reliability of a single-item quality of life and compare with the cystic fibrosis quality of life questionnaire (CF-QoL).

METHODS: Adult patients with cystic fibrosis in outpatient setting self-completed a single item quality of life scale (with a barometer anchored, from 0 - ’the worst it has ever been’ to 10 - ’the best it has ever been’) over the last 2 weeks. They also completed the CF-QoL and depression and anxiety was measured by the Hospital Anxiety Depression (HAD) Scale. Ten days later all the outcome measures were sent by post to test-retest the reliability of the single-item quality of life (single-item QoL) scale.

RESULTS: 120 cystic fibrosis patients completed the baseline measurements. Out of these, 33 cystic fibrosis patients (17 men) completed the ten days measurements. Interclass correlation coefficient (ICC) for the CF-QoL was ICC (1.1) = 0.90, 95% confidence interval 0.83 to 0.95, and single-item QOL was ICC (1.1) = 0.87, 95% confidence interval 0.74 to 0.93. The single-item QoL was correlated with the depression HAD (r = -0.38, p < 0.001), anxiety HAD (r = -50, p < 0.001), forced expiratory volume in one second (r= -21, p = 0.02), hospital admission in the previous year (r = 0.39, p < 0.0001) and all the domains of CF - QOL (p < 0.0001).

CONCLUSION: The single-item quality of scale is acceptable, valid and repeatable for patients with cystic fibrosis.

CLINICAL IMPLICATIONS: The single-item quality of life scale is a suitable and feasible scale for use in clinical practice. Further studies are needed to fully validate as a quality of life scale in the community.

DISCLOSURE: Abebaw Yohannes, No Financial Disclosure Information; No Product/Research Disclosure Information

12:45 PM - 2:00 PM




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