Poster Presentations: Wednesday, November 3, 2010 |

Influence of Respiratory Symptoms and Abnormalities on Pulmonary Function Tests in an Intensive Behavior Interventions Program for Smoking Cessation at the Hospital Universitario Professor Edgard Santos in Salvador, Brazil FREE TO VIEW

Ana Thereza C. Rocha; Manuela B. de Pinho, RT; José Franklin Pompa-Filho, MS; Marla M. Rocha, MS; Lucas S. Macedo, MS; Marina C. Cabral, MS
Author and Funding Information

Hospital Universitario Professor Edgard Santos, Salvador, Brazil

Chest. 2010;138(4_MeetingAbstracts):646A. doi:10.1378/chest.10252
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PURPOSE: To evaluate the influence of respiratory symptoms and new abnormalities on pulmonary function tests (PFT) on the rates of smoking cessation in our intensive behavior interventions program (IBI).

METHODS: We retrospectively evaluated consecutive smokers that were offered IBI by a multidisciplinary team combined with free medications. PFT were solicited from all patients with respiratory symptoms. Pearson’s chi-square was used to estimate the influence of detected abnormalities on PFT on the rates of abstinence at 1 and 3-months.

RESULTS: 350 patients were evaluated in 20 months. The FT-score was 0-4 in 26%, 5-7 in 43% and 8-10 in 31%; 262 patients started IBI (88% also used medications) and 92% had at least one respiratory complaint: cough (73%), dyspnea (69%) and wheezing (39%). PFT were performed in 242/350 patients and in 76% of those that initiated IBI, showing: normal results in 44%, small airway disease (FEF25-75% < 70%) in 10%, mild obstructive disease in 25%, moderate in 10%, severe in 2.5%, restrictive disease in 7.5% and mixed disease in 1.5%. Patients with abnormal PFT were older (56 vs. 51 years, p=0.0001), had more time of smoking (41 vs. 35 years, p=0.0001), and higher mean FT-score (6.4 vs. 5.7, p=0.04). Abstinence rate was 57% (150/262) in 1-month, 81% (150/185) in 3-months and 77% (72/94) in 6-months. The finding of obstructive and/or restrictive disease on PFT did not influence the beginning of IBI (47% vs. 54%) or the abstinence rates in 1-month (58% vs. 63%) and in 3-months (79% vs. 81%), p=NS for all.

CONCLUSION: The majority of smokers that sought treatment for nicotine-dependence presented respiratory symptoms and 46% were diagnosed with abnormalities on PFT. Patients receiving IBI with medications achieved high rates of abstinence, including those with obstructive/restrictive abnormalities.

CLINICAL IMPLICATIONS: The screening of smokers with PFT creates an opportunity for early diagnosis and treatment of pulmonary diseases and can stimulate the treatment of nicotine-dependence. IBI with medications is efficacious for smoking cessation even in older patients with new diagnosis of COPD.

DISCLOSURE: Ana Thereza Rocha, Consultant fee, speaker bureau, advisory committee, etc. I am a speaker for Pfizer.; No Product/Research Disclosure Information

12:45 PM - 2:00 PM




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