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Poster Presentations: Tuesday, November 2, 2010 |

Determination of the Utility of the Spo2/Fio2 Ratio in the Diagnosis of Patients Admitted at the Philippine Heart Center With Acute Lung Injury or Acute Respiratory Distress Syndrome: A Cross-sectional Study FREE TO VIEW

Marie Grace P. Malicdem, MD; Aileen G. Banzon, MD
Author and Funding Information

Pulmonary Division, Philippine Heart Center, Quezon City, Philippines



Chest. 2010;138(4_MeetingAbstracts):222A. doi:10.1378/chest.10229
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Abstract

PURPOSE: To determine the utility of pulse oximetric saturation (SaO2) over fraction of inspired oxygen (FiO2) as a substitute for the diagnosis of Acute Lung Injury and Acute Respiratory Distress Syndrome.

METHODS: Patients admitted at the Philippine Heart Center who were diagnosed with Acute Lung Injury and Acute Respiratory Distress Syndrome were included in the study. S/F values corresponding to P/F ratios of 200 (ARDS) and 300 (ALI) were determined. Comparison of proportions and means were done using the Fischer's exact test and student t-test, respectively.

RESULTS: There were 36 subjects included in the study. For the comparison of proportions, at the 95% level of confidence, the sensitivity value of S/F test for ARDS consistent with observed data falls at 91.7%. The specificity value of S/F test for ARDS falls at 83.3%. The positive predictive value of S/F test for ARDS falls at 91.7%. The negative predictive value of S/F test for ARDS falls at 83.3%. At 95% confidence interval, the sensitivity values of S/F test, for ALI consistent with observed data was 100%. The specificity value of S/F test for ALI was 7.7%. The positive predictive value of S/F test for ALI falls at 73.9%. The negative predictive value of S/F test for ALI falls at 100%.

CONCLUSION: Although, the number of subjects was limited, this study showed a trend toward the utility of S/F ratio as a substitute for P/F ratio for the diagnosis of Acute Lung Injury and Acute Respiratory Distress Syndrome.

CLINICAL IMPLICATIONS: In areas that lack the necessary facilities, the S/F ratio may be used as a substitute for P/F ratio for the diagnosis of Acute Lung Injury and Acute Respiratory Distress Syndrome.

DISCLOSURE: Marie Grace Malicdem, No Financial Disclosure Information; No Product/Research Disclosure Information

12:45 PM - 2:00 PM


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