PURPOSE: Obstructive sleep apnoea (OSA)is often associated with psychiatric comorbidities like depression. The objective of this study was to determine the prevalence and severity of depression and anxiety in patients of OSA at a tertiary care hospital in North India.
METHODS: Polysomnography(PSG) was performed at Sleep Laboratory of our institution(Department of Pulmonary Medicine) using Compumedics E-series-44 Channel PSG System. Forty patients diagnosed as OSA & 35 healthy controls were included in this study over one year.Patients who were already diagnosed to have a psychiatric disorder were excluded from the study. After preliminary clinical evaluation overnight PSG was done in all selected patients. The patients with Apnoea Hypopnea index (AHI) >5/hr were diagnosed as OSA and further interviewed for diagnosis of Depression & anxiety using DSM-IV (’The Diagnostic and Statistical Manual of Mental Disorders- Fourth Edition’)The severity of these disorders was analysed using Hamilton severity rating scales for depression & anxiety. The incidence of depression and anxiety was compared and categorized into different severity grades amongst cases of OSA and control subjects.
RESULTS: Ten out of 40 OSA patients(25%) were diagnosed to have depression while 1 out of 35(2.85%) healthy controls had depression(p value< 0.05). Eighteen out of 40 OSA patients(45%) had anxiety while 2 out of 35(5.71%) controls had anxiety(p value< 0.05). However the severity of depression and anxiety did not correlate with severity of OSA.(p value>0.05 for both).
CONCLUSION: The prevalence of depression and anxiety was significantly higher in patients of OSA as compared to healthy controls. Anxiety was more prevalent than depression in our group of patients.
CLINICAL IMPLICATIONS: All OSA patients should be evaluated for psychiatric disorders like depression and anxiety. Further studies with larger sample size are needed to detect the exact prevalence.
DISCLOSURE: Preeti Sharma, No Financial Disclosure Information; No Product/Research Disclosure Information