PURPOSE: Perfusion or ventilation lung scan with pulmonary function test is currently used for prediction of postoperative pulmonary function in patients undergoing major pulmonary resection. The vibratory response imaging (VRI) is a novel bedside imaging technique that displays vibration energy of lung sounds generated during the respiratory cycle as a real-time structural and functional image of the respiratory process. We measured the predicted postoperative (ppo) lung function using perfusion lung scan and VRI, and compared its results with the actual postoperative pulmonary functions results.
METHODS: Forty-four patients (28 male; mean age, 62.6±10.16 years) who were candidates for major pulmonary resection were enrolled in the study. All patients had pulmonary function test at pre and post surgery (4-6 weeks later) and the perfusion radioisotopic lung studies and VRI were performed preoperatively.
RESULTS: Forty patients had lung cancer and 4 had benign lung disease. Lobectomy was performed in 39 patients, bilobectomy in 3, and pneumonectomy in 2. Surgery was done through Video-Assisted Thoracoscopic Surgery in 25 patients or conventional thoracotomy in 19. VRI measurements were correlated well with perfusion measurements of ppo FEV1 (r=0.93, p<0.001) and %DLco (r =0.90, p<0.001). The ppo FEV1 measured by VRI (r=0.83, p<0.001) and by perfusion scan (r=0.81, p<0.001) were equally correlated with the actual postoperative result. And, both ppo %DLco measured by VRI (r =0.38, p<0.05) and by perfusion scan (r =0.37, p<0.05) were correlated with the actual postoperative result.
CONCLUSION: VRI may be a good alternative in prediction of postoperative pulmonary function test. Furthermore, it is computer-based, radiation-free device intended for non-invasive recording, thus posing no risk to patients.
CLINICAL IMPLICATIONS: Non-invasive VRI could be used in prediction of postoperative pulmonary function for patients undergoing major pulmonary resection.
DISCLOSURE: Hyun Koo Kim, No Financial Disclosure Information; No Product/Research Disclosure Information