0
Poster Presentations: Tuesday, November 2, 2010 |

Contemporary Trends in the Diagnosis and Management of PAH: An Initiative To Close the Care Gap FREE TO VIEW

Vallerie V. McLaughlin, MD; Anatoly Langer, MD; Alina Dragomir, MD; Amparo Casanova, MD; Mary Tan, BSc; Philip J. Clements, MD; Ronald J. Oudiz, MD; Victor F. Tapson, MD; Richard N. Channick, MD; Lewis J. Rubin, MD
Author and Funding Information

Canadian Heart Research Centre, Toronto, ON, Canada



Chest. 2010;138(4_MeetingAbstracts):351A. doi:10.1378/chest.9901
Text Size: A A A
Published online

Abstract

PURPOSE: The Pulmonary Arterial Hypertension Quality Enhancement Research Initiative (PAH-QuERI) was set up to support clinicians and facilitate a guideline based approach to PAH.

METHODS: Between October 2005 and June 2007, 62 US specialist practices participated. Physicians recorded patient work up, management, and outcome data into an electronic data management system. Queries were generated automatically at each of the prescheduled follow-up visits if the guideline recommended tests were not performed at least once.

RESULTS: Of 787 patients 77.5% were women, 55 years old (45, 66), 8.6% were in class I, 38.8% in II, 47.5% in III, and 5.1% in IV .Of the ACCP recommended work up variables at baseline, CBC was performed in 90.7%, LFT in 90.6%, CTD screen in 50.2%, HIV screen in 29.0%, CXR in 88.3%, ECG in 81.6%, PFT in 2.8%, V/Q scan in 57.4%, 2-D Echo in 96.8%, 6MW in 76.0%, and RHC in 90.3% of patients. The quality enhancement component of this program generated 1494 reminders on 636 patients (80.8%) with validated baseline data. A majority of patients had one reminder (median of 2 reminders (1, 3)) resulting in proportion of patients in whom a recommended ACCP test was not done at baseline but was done at 6 or 12-month follow up visit. All recommended tests (CXR, ECG and Echo) were performed in 73.7%. With respect to management, 77.8% of patients were on disease specific therapy. Calcium blockers were used in 21.6% and approximately half were on this therapy specifically for PAH. While RHC was performed in the majority of these patients, the vasoreactivity was assessed in only 36.5% and was positive in only 8.2%.

CONCLUSION: The PAH-QuERI database allows a real world look at the diagnosis, management and outcome in PAH patients. The results suggest that PAH work-up and management may be suboptimal for some patients but can be improved through educational initiatives.

CLINICAL IMPLICATIONS: Greater adherence to guidelines may improve outcome in these high-risk patients.

DISCLOSURE: Anatoly Langer, Grant monies (from industry related sources) Actelion has provided reserach grant for this work.; No Product/Research Disclosure Information

12:45 PM - 2:00 PM


Figures

Tables

References

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.

  • CHEST Journal
    Print ISSN: 0012-3692
    Online ISSN: 1931-3543