Poster Presentations: Wednesday, November 3, 2010 |

Prevalence of Alveolar Hypoventilation in 36,444 Patients Presenting for Evaluation of a Sleep Complaint FREE TO VIEW

Jo Anne Turner, APRN-BC; Richard K. Bogan, MD
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SleepMed, Columbia, SC

Chest. 2010;138(4_MeetingAbstracts):622A. doi:10.1378/chest.9418
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PURPOSE: In a group of patients presenting for sleep evaluation with PSG, an effort is made to examine prevalence of alveolar hypoventilation syndrome (AH) and review demographics as well as sleepiness. Epworth Sleepiness Scale (ESS) is a validated tool measuring excessive daytime sleepiness (EDS).

METHODS: 36344 baseline PSGs from 2009-2010 at SleepMed were reviewed. ESS was administered prior to each study. Oxygen desaturation index (ODI) was measured at equal to or greater than the 4% level during the total sleep time as well as saturation index time less than 90%. Patients were selected with low RDI but sustained desaturation. Comparison was made with patients RDI >20 without regard to ODI.

RESULTS: For all studied there were 17810 females (49%) and 18534 males (51%) with mean age of 50 (18). Means and standard deviations: ESS score= 9.58 (6); BMI= 32(10); RDI= 20 (22); ODI= 13 (18); nadir oxygen= 84 (8); time< 90% (min) = 33 (61). For AH with RDI< 10, nadir oxygen less than 85%, time below 90% > 10 minutes, ODI < 10/hour there were 1470 (4%)/36344. 951(65%) females 519 (35%) males with mean age of 56 (16). ESS score= 9.8 (6); BMI= 33(9); RDI= 6 (3); nadir oxygen=80 (29); ODI =4 (2); time< 90% (min) =103(100). For OSA RDI>20 there were 12151/36344 (33%). 4432 females (36%); 7782 males (64%); mean age= 56(15). ESS score =10 (6); BMI= 35(12); RDI= 44 (22); nadir oxygen=79(9); time< 90%= 48 minutes (66); ODI 30 (22). In OSA group 1470/12515 (12%) have AH. T-tests: ESS scores of AH to OSA p=0.15; AH to all studied p=0.24; OSA to all studied p=1.48E-14.

CONCLUSION: 4% of all patients and 12% of OSA group presenting with a sleep complaint were found to have features of AH as measured by saturation index time below 90% with low RDI and are sleepy as measured by ESS. There was a female preponderance in AH with male in OSA.

CLINICAL IMPLICATIONS: Identification of correlates and prevalence of AH will assist the clinician in diagnosis.

DISCLOSURE: Jo Anne Turner, No Financial Disclosure Information; No Product/Research Disclosure Information

12:45 PM - 2:00 PM




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