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Poster Presentations: Tuesday, November 2, 2010 |

Predicting Fluid Responsiveness With Passive Leg Raising Test in Patients With Septic Shock FREE TO VIEW

Nimit Buranasing, MD; Anan Wattanathum, MD
Author and Funding Information

Division of Pulmonary and Critical Care, Department of Medicine, Phramongkutklao, Bangkok, Thailand



Chest. 2010;138(4_MeetingAbstracts):215A. doi:10.1378/chest.9395
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Abstract

PURPOSE: To evaluate an efficacy of PLRT in critically ill, mechanical ventilated patients with septic shock and evaluate an accuracy of Vigileo(r) in comparison with the PiCCO(r).

METHODS: A prospective study was conducted during April-November 2009 on a basis of patients with norepinephrine and haemodynamic monitoring by Flo-Trac/Vigileo(r) and PiCCO(r) with a transpulmonary thermodilution technique. A paired t-test, mean+SD and ROC curve were used for statistical analysis.

RESULTS: 15 patients were studied, 12 of which were male with an average age of 60.3±22.9. Norepinephrine was 0.42+0.37 μ g/kg/min. The mean arterial pressure was 72.73±10.23 mmHg at a baseline, 71.33±12.75 mmHg at PLRT and 76.9±13 mmHg at the post-volume expansion. CVP was 9.07±5.02 mmHg at a baseline, 10.6±4.29 mmHg at the PLRT and 13.7±5.6 mmHg at the post-volume expansion. CI was 4.1±1.4 l/min/m2at a baseline, 4.2±1.5 l/min/m2at PLRT and 4.3±1.6 l/min/m2at the post-volume expansion. 6 patients were the responders of the post-volume expansion with cardiac index change over 15% with the PiCCO(r) system. The PLRT of the PiCCO(r) system with cardiac index change over 5.28% (50% sensitivity and 78% specificity) and the PLRT of the Flo-Trac/Vigileo(r) system with cardiac index change over 4.32% (50% sensitivity and 89% specificity) were the responders.

CONCLUSION: The PLRT results showed that this method can be used to determine the value lesser than that used in the previous studies. The measurement of CI using a non-calibrated pulse contour analysis system (Flo-Trac and Vigileo(r)) and calibrated system (PiCCO(r)) is not significantly different.

CLINICAL IMPLICATIONS: The PLRT results showed that this method can be used to determine the value lesser than that used in the previous studies. The measurement of CI using a non-calibrated pulse contour analysis system (Flo-Trac and Vigileo(r)) and calibrated system (PiCCO(r)) is not significantly different.

DISCLOSURE: Nimit Buranasing, No Financial Disclosure Information; No Product/Research Disclosure Information

12:45 PM - 2:00 PM


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