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Legionnaires Disease in Cannabis Smokers

Lan Tien Nguyen, MD; Valérie Picard-Bernard, MD; Jean Perriot, MD
Author and Funding Information

From the Service de Pneumologie, Unité d’Addictologie (Dr Nguyen), CH Jacques Lacarin, Vichy; the Service de Psychiatrie Adultes, Unité d’Addictologie (Dr Picard-Bernard), CH Thiers; and the Dispensaire Emile Roux (Dr Perriot), Clermont Ferrand, France.

Correspondence to: Lan Tien Nguyen, MD, Service de Pneumologie, Unité d’Addictologie, CH Jacques Lacarin, BP 2757, 03207 Vichy Cedex, France; e-mail: lantien.nguyen@ch-vichy.fr


Reproduction of this article is prohibited without written permission from the American College of Chest Physicians (http://www.chestpubs.org/site/misc/reprints.xhtml).


© 2010 American College of Chest Physicians


Chest. 2010;138(4):989-991. doi:10.1378/chest.10-0410
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Tobacco smoking is a well-recognized risk factor for Legionnaires disease. However, it may be potentiated by cannabis use, as there is strong evidence that Δ9-tetrahydrocannabinol impairs immune functions in vitro and in vivo. We report herein two out of three cases of severe Legionnaires disease in three men with no overt comorbid illnesses, aged 38, 28, and 48 years, respectively. All of them were heavy cigarette and cannabis smokers.

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