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Editorials |

“All That Glitters…”: Evaluating Interventions for Emphysema

Joel D. Cooper, MD, FCCP
Author and Funding Information

From the Division of Thoracic Surgery, The University of Pennsylvania Health System.

Correspondence to: Joel D. Cooper, MD, FCCP, Division of Thoracic Surgery, The Hospital of the University of Pennsylvania, 6 White, 3400 Spruce St, Philadelphia, PA 19104; e-mail: joel.cooper@uphs.upenn.edu


Financial/nonfinancial disclosure: The author has reported to CHEST the following conflict of interest: Dr Cooper receives a royalty from Synovis Life Technologies for the development of the Peri-Strip staple line reinforcement used by some surgeons for lung volume reduction surgery. Prior to one year ago the author was a paid consultant for Broncus Technologies, Inc and Emphasys Medical, Inc.

Reproduction of this article is prohibited without written permission from the American College of Chest Physicians (www.chestpubs.org/site/misc/reprints.xhtml).


© 2010 American College of Chest Physicians


Chest. 2010;138(2):243-245. doi:10.1378/chest.10-0829
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Extract

In this issue of CHEST (see page 407), Berger and coauthors1 highlight a significant hurdle for the development of new interventional treatments for emphysema. Specifically, can standard outcome measures be developed to validate the benefit of such interventions? The authors review clinical trials for one surgical procedure, lung volume reduction surgery (LVRS), and four bronchoscopic procedures, all designed to improve dyspnea and quality of life for patients with this common, debilitating, and often fatal disease. Despite common goals, the pathways for each have differed with respect to patient selection, clinical trials, and end points.

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