Epidemiologic studies have suggested that a relationship may exist between self-reported restless legs syndrome (RLS) and hypertension.24 Ohayon and Roth25 examined RLS prevalence in a cross-sectional population study of 18,980 subjects aged ≥ 15 years in five European countries through a telephone interview. Hypertension (treated or untreated) was significantly associated with RLS (P < .001) and made an independent significant contribution to RLS (OR, 1.36; 95% CI, 1.14-1.61; P < .001) but not to periodic limb movements in sleep (PLMS).25 Of note, the diagnosis of PLMS was not made by polysomnography but by the validated Sleep-EVAL system questionnaire, which has a κ for diagnosing PLMS of 0.84.25 Likewise, Phillips et al26 examined RLS prevalence and correlates as part of the 2005 National Sleep Foundation Poll, a telephone interview of 1,506 randomly selected adults in the United States. Hypertension was associated with RLS (P < .05). Ulfberg et al27 examined by questionnaire a random population sample of 4,000 men living in central Sweden, finding that subjects with reported RLS symptoms more frequently reported hypertension (OR, 1.15; 95% CI, 0.9-2.4). Examining the 3,433 men and women enrolled in the Sleep Heart Health Study, Winkelman et al28 also noted only a weak association of RLS with hypertension (OR, 1.30; 95% CI, 0.92-1.82) after adjusting for age, sex, race, and BMI.