A 49-year-old black woman with sickle cell disease (SCD) presented to the ED complaining of severe left lower extremity pain. She was diagnosed with vasoocclusive crisis and admitted for IV hydration and analgesia. She remained hemodynamically stable for the first 14 days. On the 15th day of hospitalization, she began complaining of acute dyspnea and chest pain, and a rapid response was initiated.
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