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Postgraduate Education Corner: PULMONARY AND CRITICAL CARE PEARLS |

A 49-Year-Old Woman With Acute Respiratory Failure

Zachary S. DePew, MD; Wilson Gonsalves, MD; Dan Schuller, MD, FCCP
Author and Funding Information

From the Department of Internal Medicine (Drs DePew, Gonsalves, and Schuller), and the Pulmonary, Critical Care, and Sleep Medicine Division (Dr Schuller), Creighton University Medical Center, Omaha, NE.

Correspondence to: Dan Schuller, MD, Pulmonary, Critical Care, and Sleep Medicine Division, Creighton University Medical Center, 601 N 30th St, Ste 3820, Omaha, NE 68131; e-mail: schuller@creighton.edu


Reproduction of this article is prohibited without written permission from the American College of Chest Physicians (www.chestpubs.org/site/misc/reprints.xhtml).


© 2010 American College of Chest Physicians


Chest. 2010;138(1):224-227. doi:10.1378/chest.09-2942
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Extract

A 49-year-old black woman with sickle cell disease (SCD) presented to the ED complaining of severe left lower extremity pain. She was diagnosed with vasoocclusive crisis and admitted for IV hydration and analgesia. She remained hemodynamically stable for the first 14 days. On the 15th day of hospitalization, she began complaining of acute dyspnea and chest pain, and a rapid response was initiated.

LesterLASodtPCHutcheonNArcillaRACardiac abnormalities in children with sickle cell anemiaChest199098511691174NorrisSJohnsonCSHaywoodLJSickle cell anemia: does myocardial ischemia occur during crisis?J Natl Med Assoc1991833209213WayneASKevySVNathanDGTransfusion management of sickle cell diseaseBlood199381511091123PlattOSBrambillaDJRosseWFMortality in sickle cell disease. Life expectancy and risk factors for early deathN Engl J Med19943302316391644BelletPSKalinyakKAShuklaRGelfandMJRucknagelDLIncentive spirometry to prevent acute pulmonary complications in sickle cell diseasesN Engl J Med199533311699703EmreUMillerSTGutierezMSteinerPRaoSPRaoMEffect of transfusion in acute chest syndrome of sickle cell diseaseJ Pediatr19951276901904PlattOSThe acute chest syndrome of sickle cell diseaseN Engl J Med20003422519041907VichinskyEPNeumayrLDEarlesANNational Acute Chest Syndrome Study GroupCauses and outcomes of the acute chest syndrome in sickle cell diseaseN Engl J Med20003422518551865RamanSVSimonettiOPCatalandSRKrautEHMyocardial ischemia and right ventricular dysfunction in adult patients with sickle cell diseaseHaematologica2006911013291335GladwinMTVichinskyEPulmonary complication of sickle cell diseaseN Engl J Med200835921225465

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