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Postgraduate Education Corner |

A 24-Year-Old Man With Mediastinal Mass, Dyspnea, and a Pleural Effusion*

Anthony S. Rose, MD; Kenneth S. Knox, MD, FCCP; Chadi A. Hage, MD, FCCP
Author and Funding Information

*From the Division of Pulmonary and Critical Care Medicine (Dr. Rose) and Roudebush VA Medical Center (Drs. Knox and Hage), Indiana University Medical Center, Indianapolis, IN.

Correspondence to: Anthony S. Rose, MD, 1481 West Tenth St, VA 111P-IU, Indianapolis, IN 46202; e-mail: asrose@iupui.edu


Chest. 2008;134(1):200-203. doi:10.1378/chest.07-2487
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In 2002, a 24-year-old man was referred to our clinic for mild exertional dyspnea and nonproductive cough that had slowly developed over 2 years. He had no hemoptysis, fevers, or weight loss, and had never used tobacco. He reported no history of travel outside of the Midwest. His medical history was otherwise unremarkable.

1Davis, AM, Pierson, RN, Loyd, JE (2001) Mediastinal fibrosis.Semin Respir Infect16,119-1302Doyle, TP, Loyd, JE, Robbins, IM Percutaneous pulmonary artery and vein stenting: a novel treatment for mediastinal fibrosis.Am J Respir Crit Care Med2001;164,657-6603Mathisen, DJ, Grillo, HC Clinical manifestation of mediastinal fibrosis and histoplasmosis.Ann Thorac Surg1992;54,1053-1057discussion 1057–10584Routsi, C, Charitos, C, Rontogianni, D, et al Unilateral pulmonary edema due to pulmonary venous obstruction from fibrosing mediastinitis.Int J Cardiol2006;108,418-4215Sherrick, AD, Brown, LR, Harms, GF, et al The radiographic findings of fibrosing mediastinitis.Chest1994;106,484-4896Wheat, LJ, Freifeld, AG, Kleiman, MB, et al Clinical practice guidelines for the management of patients with histoplasmosis: 2007 update by the Infectious Diseases Society of America.Clin Infect Dis2007;45,807-825

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