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Editorials: POINT/COUNTERPOINT EDITORIALS |

Rebuttal From Dr. Guyatt et al

Gordon H. Guyatt, MD, MSc, FCCP; Paul J. Karanicolas, MD; Regina Kunz, MD, PhD
Author and Funding Information

Affiliations: Hamilton, ON, Canada,  Basel, Switzerland

Correspondence to: Gordon H. Guyatt, MD, MSc, FCCP, Department of Clinical Epidemiology and Biostatistics, McMaster University Medical Center, 1200 Main St West, Room 2C12, Hamilton, ON, L8N 3Z5 Canada; e-mail: guyatt@mcmaster.ca



Chest. 2008;133(5):1074-1075. doi:10.1378/chest.08-0194
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It is unfortunate that Dr. Tobin1 (see page 1071) relied largely on early writings about evidence-based medicine (EBM). For instance, when considering the EBM approach to quality of evidence (Table 2 in the editorial by Tobin1), he uses a 1995 publication rather than the most recent approaches.25 In our response, we will use the system of evaluating evidence and developing recommendations that has been proposed by the Grading of Recommendations Assessment, Development and Evaluation (GRADE) Working Group24 and the American College of Chest Physicians,5 which reflects the current thinking on EBM. We quote Dr. Tobin's misguided notions about EBM; what EBM actually maintains follows the quotations.

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