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Postgraduate Education Corner |

A 40-Year-Old Man With Neutropenic Fever and Lobar Consolidation*

Aaron Holley, MD; Danira Mayes, MD; Robert Browning, MD
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*From the Walter Reed Army Medical Center (Drs. Holley and Mayes), Washington, DC; and National Naval Medical Center (Dr. Browning), Bethesda, MD.

Correspondence to: Aaron Holley, MD, Walter Reed Army Medical Center, 6900 Georgia Ave NW, Washington, DC 20307; e-mail: aaron.holley@NA.amedd.army.mil


Chest. 2008;133(3):816-819. doi:10.1378/chest.07-1627
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1Peikert, T, Rana, S, Edell, E (2005) Safety, diagnostic yield, and therapeutic implications of flexible bronchoscopy in patients with febrile neutropenia and pulmonary infiltrates.Mayo Clin Proc80,1414-14202Gruson, D, Hilbert, G, Valentino, R, et al Utility of fiberoptic bronchoscopy in neutropenic patients admitted to the intensive care unit with pulmonary infiltrates.Crit Care Med2000;28,2224-22303Rosenow, EC, Wilson, WR, Cockeril, FR Pulmonary disease in the immunocompromised host.Mayo Clin Proc1985;60,473-4874Rosenow, EC Diffuse pulmonary infiltrates in the immunocompromised host.Clin Chest Med1990;11,55-645Ewig, S, Glasmacher, A, Ulrich, B, et al Pulmonary infiltrates in neutropenic patients with acute leukemia during chemotherapy: outcome and prognostic factors.Chest1998;114,444-4516Hughes, WT, Armstrong, D, Bodey, GP, et al 2002 guidelines for the use of antimicrobial agents in neutropenic patients with cancer.Clin Infect Dis2002;34,730-7517Heussel, CP, Kauczor, HU, Heussel, GE, et al Pneumonia in febrile neutropenic patients and in bone marrow and blood stem cell transplant recipients: use of high resolution computed tomography.J Clin Oncol1999;17,796-8058Lee, FYW, Mossad, FB, Adal, KA Pulmonary mucormycosis.Arch Intern Med1999;159,1301-13099Jaffe, JP, Maki, DG Lung biopsy in immunocompromised patients: one institution’s experience and an approach to management of pulmonary disease in the compromised host.Cancer1981;48,1144-115310Janzen, DL, Adler, BD, Padley, SP, et al Diagnostic success of bronchoscopic biopsy in immunocompromised patients with acute pulmonary disease: predictive value of disease distribution as shown on CT.AJR Am J Roentgenol1993;160,21-2411Jain, P, Sandur, S, Meli, Y, et al Role of flexible bronchoscopy in immunocompromised patients with lung infiltrates.Chest2004;125,712-72212Meyer, RD, Rosen, P, Armstrong, D Phycomycosis complicating leukemia and lymphoma.Ann Intern Med1972;77,871-87913McAdams, HP, de Christenson, MR, Strollo, DC, et al Pulmonary mucormycosis: radiologic findings in 32 cases.AJR Am J Roentgenol1997;168,1541-154814Greene, RE, Schlamm, HT, Oestmann, JW, et al Imaging findings in acute invasive pulmonary aspergillosis: clinical significance of the halo sign.Clin Infect Dis2007;44,373-37915Primack, SL, Hartman, TE, Lee, KS, et al Pulmonary nodules and the CT halo sign.Radiology1994;190,513-51516Chonga, S, Lee, KS, Yia, CA, et al Pulmonary fungal infection: imaging findings in immunocompetent and immunocompromised patients.Eur J Radiol2006;59,371-38317Gefter, WB, Albelda, SM, Talbot, GH, et al Invasive aspergillosis and acute leukemia: limitations in the diagnostic utility of the air crescent sign.Radiology1985;157,605-61018Sugar, AM, Olek, EA Fishman’s pulmonary diseases and disorders 3rd ed.1998,2281-2284 McGraw-Hill. New York, NY:

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