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Postgraduate Education Corner: CASE RECORDS OF THE UNIVERSITY OF COLORADO |

A 64-Year-Old Woman With a History of Rheumatoid Arthritis and New Cavitary Lung Lesions*

Darren M. Boé, MD, PhD, FCCP; Marvin I. Schwarz, MD, FCCP; Steve D. Groshong, MD, PhD; James P. Maloney, MD
Author and Funding Information

*From the Division of Pulmonary Sciences and Critical Care Medicine (Drs. Boé, Schwarz, and Maloney), University of Colorado Health Sciences Center; and Department of Pathology (Dr. Groshong), National Jewish Medical and Research Center, Denver, CO.

Correspondence to: Darren M. Boé, MD, PhD, FCCP, Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Health Sciences Center, 4200 E Ninth Ave, C272, Denver, CO 80262; e-mail: Darren.boe@uchsc.edu



Chest. 2007;132(6):2046-2052. doi:10.1378/chest.07-2058
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1Charles, PJ, Maini, RN (1993) Antibodies to neutrophil cytoplasmic antigens in rheumatoid arthritis.Adv Exp Med Biol336,367-3702Covic, A, Mutica, C, Ignat, A, et al Retrospective study of 97 ANCA-positive patients: epidemiologic and clinical spectrum [in Romanian].Rev Med Chir Soc Med Nat Iasi2004;108,305-3103Douglas, G, Bird, K, Flume, P, et al Wegener’s granulomatosis in patients with rheumatoid arthritis.J Rheumatol2003;30,2064-20694Hagen, EC, Daha, MR, Hermans, J, et al Diagnostic value of standardized assays for anti-neutrophil cytoplasmic antibodies in idiopathic systemic vasculitis: EC/BCR Project for ANCA Assay Standardization.Kidney Int1998;53,743-7535Anaya, JM, Diethelm, L, Ortiz, LA, et al Pulmonary involvement in rheumatoid arthritis.Semin Arthritis Rheum1995;24,242-2546Cordier, JF, Valeyre, D, Guillevin, L, et al Pulmonary Wegener’s granulomatosis: a clinical and imaging study of 77 cases.Chest1990;97,906-9127Noritake, DT, Weiner, SR, Bassett, LW, et al Rheumatic manifestations of Wegener’s granulomatosis.J Rheumatol1987;14,949-9518Ohashi, H, Itoh, M, Ogawa, N, et al Wegener’s granulomatosis in a patient with a rheumatoid arthritis.Intern Med1992;31,1128-11319Pritchard, MH Wegener’s granulomatosis presenting as rheumatoid arthritis (two cases).Proc R Soc Med1976;69,501-50410Sturrock, RD, Ratnesar, P Wegener’s granulomatosis occurring in a patient with pre-existing rheumatoid arthritis.Br J Clin Pract1974;28,183-18411Chinoy, H, McKenna, F Wegener’s granulomatosis and rheumatoid arthritis overlap.Rheumatology (Oxford)2002;41,588-58912Hoffman, GS, Kerr, GS, Leavitt, RY, et al Wegener granulomatosis: an analysis of 158 patients.Ann Intern Med1992;116,488-49813Jacobs, RP, Moore, M, Brower, A Wegener’s granulomatosis presenting with erosive arthritis.Arthritis Rheum1987;30,943-94614Leavitt, RY, Fauci, AS, Bloch, DA, et al The American College of Rheumatology 1990 criteria for the classification of Wegener’s granulomatosis.Arthritis Rheum1990;33,1101-110715Stone, JH Limited versus severe Wegener’s granulomatosis: baseline data on patients in the Wegener’s granulomatosis etanercept trial.Arthritis Rheum2003;48,2299-230916Seo, P, Stone, JH The antineutrophil cytoplasmic antibody-associated vasculitides.Am J Med2004;117,39-5017Coremans, IE, Hagen, EC, Daha, MR, et al Antilactoferrin antibodies in patients with rheumatoid arthritis are associated with vasculitis.Arthritis Rheum1992;35,1466-147518Fauci, AS, Haynes, BF, Katz, P, et al Wegener’s granulomatosis: prospective clinical and therapeutic experience with 85 patients for 21 years.Ann Intern Med1983;98,76-8519Reza, MJ, Dornfeld, L, Goldberg, LS, et al Wegener’s granulomatosis: long-term followup of patients treated with cyclophosphamide.Arthritis Rheum1975;18,501-506

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