A 21-year-old man with hemoglobin SC disease presented to the emergency department with backache and bilateral knee pain. The patient had been practicing sports for 2 h before symptoms started. The pain was sharp and severe in intensity, and it was localized to the thoracic spine and both knees. He went to the emergency department after 30 min of persistent pain. The patient had had two episodes of mild backache and knee pain as a child and remained asymptomatic ever since. The patient was not taking any medications on a regular basis.