0
Clinical Practice Guidelines |

Medical Therapy for Pulmonary Arterial Hypertension*: Updated ACCP Evidence-Based Clinical Practice Guidelines

David B. Badesch, MD, FCCP; Steven H. Abman, MD; Gerald Simonneau, MD; Lewis J. Rubin, MD, FCCP; Vallerie V. McLaughlin, MD, FCCP
Author and Funding Information

*From the University of Colorado Health Sciences Center (Dr. Badesch), Denver, CO; The Children’s Hospital (Dr. Abman), Denver, CO; Hôpital Antoine Béclère (Dr. Simonneau), Clamart, France; University of California, San Diego (Dr. Rubin), San Diego, CA; and University of Michigan (Dr. McLaughlin), Ann Arbor, MI.

Correspondence to: David B. Badesch, MD, FCCP, University of Colorado Health Sciences Center, Box C-272, 4200 E. Ninth Ave, Denver, CO 80262; e-mail: David.Badesch@UCHSC.edu



Chest. 2007;131(6):1917-1928. doi:10.1378/chest.06-2674
Text Size: A A A
Published online

A consensus panel convened by the American College of Chest Physicians developed guidelines for the treatment of pulmonary arterial hypertension (PAH) that were published in 2004. Subsequently, several important clinical trials have been published, and new treatments have received regulatory approval. In addition, add-on and combination therapy are being explored, which promise to open new therapeutic avenues. This article, taking into consideration studies published prior to September 1, 2006, provides an update to the previously published guidelines. The original guidelines have been summarized, a discussion of new studies has been added, and the treatment algorithm has been revised to take into account recent developments in therapy. This update provides evidence-based treatment recommendations for physicians involved in the care of patients with PAH. Due to the complexity of the diagnostic evaluation required and the treatment options available, referral of patients with PAH to a specialized center continues to be strongly recommended.

Figures in this Article

Sign In to Access Full Content

MEMBER & INDIVIDUAL SUBSCRIBER

Want Access?

NEW TO CHEST?

Become a CHEST member and receive a FREE subscription as a benefit of membership.

Individuals can purchase this article on ScienceDirect.

Individuals can purchase a subscription to the journal.

Individuals can purchase a subscription to the journal or buy individual articles.

Learn more about membership or Purchase a Full Subscription.

INSTITUTIONAL ACCESS

Institutional access is now available through ScienceDirect and can be purchased at myelsevier.com.

Sign In to Access Full Content

MEMBER & INDIVIDUAL SUBSCRIBER

Want Access?

NEW TO CHEST?

Become a CHEST member and receive a FREE subscription as a benefit of membership.

Individuals can purchase this article on ScienceDirect.

Individuals can purchase a subscription to the journal.

Individuals can purchase a subscription to the journal or buy individual articles.

Learn more about membership or Purchase a Full Subscription.

INSTITUTIONAL ACCESS

Institutional access is now available through ScienceDirect and can be purchased at myelsevier.com.

Figures

Tables

References

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

MEMBER & INDIVIDUAL SUBSCRIBER

Want Access?

NEW TO CHEST?

Become a CHEST member and receive a FREE subscription as a benefit of membership.

Individuals can purchase this article on ScienceDirect.

Individuals can purchase a subscription to the journal.

Individuals can purchase a subscription to the journal or buy individual articles.

Learn more about membership or Purchase a Full Subscription.

INSTITUTIONAL ACCESS

Institutional access is now available through ScienceDirect and can be purchased at myelsevier.com.

Related Content

Customize your page view by dragging & repositioning the boxes below.

CHEST Journal Articles
Medical Therapy For Pulmonary Arterial Hypertension*: ACCP Evidence-Based Clinical Practice Guidelines
PubMed Articles
  • CHEST Journal
    Print ISSN: 0012-3692
    Online ISSN: 1931-3543