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Editorials |

Bronchoscopic Cytology : Expanding the Menu

Dani S. Zander, MD
Author and Funding Information

Affiliations: Hershey, PA
 ,  Dr. Zander is Professor and Chair of the Department of Pathology, Penn State Milton S. Hershey Medical Center.

Correspondence to: Dani S. Zander, MD, Professor and Chair, Department of Pathology, Penn State Milton S. Hershey Medical Center, M.C. H083, PO Box 850, 500 University Dr, Hershey, PA 17033-0850; e-mail: dzander@hmc.psu.edu



Chest. 2006;130(3):634-635. doi:10.1378/chest.130.3.634
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Over the last several years, molecular technologies have come to occupy a portion of center stage in the evaluation of cytologic samples. These techniques have been particularly beneficial in the area of gynecologic cytology. The testing of liquid-based cervicovaginal cytology specimens for human papillomavirus has enhanced the effectiveness of the pap smear as a screening test for cervical malignancy and its precursor lesions, and has been recommended for most women ≥ 30 years of age. This testing allows for the identification of patients who are at higher risk for cervical cancer and provides assistance to practitioners dealing with indeterminate cytology interpretations such as “atypical squamous cells of undetermined significance,” which is a heterogeneous diagnostic category that includes examples of dysplasia, reactive changes, and atrophy.

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