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Editorials |

Cooling the Fire Within : Inhaled Corticosteroids and Cardiovascular Mortality in COPD

Don D. Sin, MD, FCCP; S.F. Paul Man, MD, FCCP
Author and Funding Information

Affiliations: Vancouver, BC, Canada
 ,  Drs. Sin and Man are affiliated with the James Hogg iCAPTURE Center for Cardiovascular and Pulmonary Research, St. Paul’s Hospital, and the Department of Medicine (Division of Respirology), The University of British Columbia.

Correspondence to: Don D. Sin, MD, FCCP, James Hogg iCAPTURE Center for Cardiovascular and Pulmonary Research, St. Paul’s Hospital, Room 368A, 1081 Burrard St, Vancouver, BC V6Z 1Y6, Canada; e-mail: dsin@mrl.ubc.ca



Chest. 2006;130(3):629-631. doi:10.1378/chest.130.3.629
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COPD is a worldwide epidemic, killing nearly 3 million people annually worldwide.1 Since 1965, the age-adjusted mortality rates for COPD have jumped by > 163%, representing the largest increase in mortality rates among all major causes of death in the Western world.2 Sadly, even the most optimistic estimates suggest that COPD mortality rates will increase by 50% over the next 15 years.1 Until now, aside from smoking cessation and supplemental oxygen therapy for hypoxic patients, no pharmacologic therapies have been demonstrated to enhance survival in COPD patients.3

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