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Postgraduate Education Corner: PULMONARY AND CRITICAL CARE PEARLS |

Acute Tachypnea During Mechanical Ventilation in a 62-Year-Old Man With Multiple Myeloma Involving the Spinal Cord*

Nuala J. Meyer, MD; Steven Q. Davis, MD; John P. Kress, MD
Author and Funding Information

*From the Section of Pulmonary and Critical Care Medicine, University of Chicago, Chicago, IL.

Correspondence to: John Kress, MD, University of Chicago, Department of Medicine, Section of Pulmonary and Critical Care, 5841 South Maryland Ave, MC6026, Chicago, IL 60637; e-mail: jkress@medicine.bsd.uchicago.edu



Chest. 2006;130(2):616-619. doi:10.1378/chest.130.2.616
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A 62-year-old man with a history of multiple myeloma was admitted to the medical ICU with respiratory failure due to respiratory muscle weakness. His myeloma had been diagnosed 4 months earlier, when he had presented with a lumbar cord compression and underwent urgent laminectomy. His pathologic specimen revealed myeloma invading the epidural fat. He had undergone 4 months of therapy with dexamethasone and thalidomide, was walking unassisted, and was independent in his activities of daily living. At the time of the present hospital admission, his family described a history of progressive ascending motor weakness over a 6-week period to the point that he was unable to walk.

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