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Postgraduate Education Corner: PULMONARY AND CRITICAL CARE PEARLS |

An 18-Year-Old Man With Rapidly Progressive Multiorgan Failure After a Positive Mononucleosis Spot Test Result*

Hanneke J. van der Woude, MD, PhD; Tjip S. van der Werf, MD, PhD; Eric A. M. Verschuuren, MD, PhD; Rienk Y. J. Tamminga, MD, PhD; Stefano Rosati, MD, PhD; John H. J. M. Meertens, MD; Jan G. Zijlstra, MD, PhD
Author and Funding Information

*From the Department of Internal Diseases (Drs. van der Woude, van der Werf, Verschuuren, Meertens, and Zijlstra), Beatrix Children’s Hospital (Dr. Tamminga), and Department of Pathology (Dr. Rosati), Universitair Medisch Centrum Groningen, Groningen, the Netherlands.

Correspondence to: Tjip S. van der Werf, MD, PhD, Universitair Medisch Centrum Groningen, Intensive and Respiratory Care Unit, Department of Internal Diseases, Hanzeplein 1, 9713 GZ Groningen, the Netherlands; e-mail: t.s.van.der.werf@int.umcg.nl



Chest. 2006;130(1):291-295. doi:10.1378/chest.130.1.291
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An 18-year-old man was transferred to our ICU because of progressive renal and hepatic failure. Three weeks earlier, he had been admitted to another hospital because of a 1-week history of fever, headache, soar throat, enlarged lymph nodes, and a positive mononucleosis spot test result suggesting infection with Epstein-Barr virus (EBV). He denied smoking and drinking alcohol. He was single. He was working as a market vendor and was learning to become a driving instructor. He had not traveled abroad.

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