An 18-year-old man was transferred to our ICU because of progressive renal and hepatic failure. Three weeks earlier, he had been admitted to another hospital because of a 1-week history of fever, headache, soar throat, enlarged lymph nodes, and a positive mononucleosis spot test result suggesting infection with Epstein-Barr virus (EBV). He denied smoking and drinking alcohol. He was single. He was working as a market vendor and was learning to become a driving instructor. He had not traveled abroad.