0
Editorials |

Transbronchial Biopsy and Usual Interstitial Pneumonia: A New Paradigm?

Andrew Churg, MD; Marvin Schwarz, MD, FCCP
Author and Funding Information

Affiliations: Vancouver, BC, Canada
 ,  Denver, CO
 ,  Dr. Churg is Professor, Department of Pathology, University of British Columbia, Vancouver, BC; and Dr. Schwarz is the James C. Campbell Professor, Department of Medicine, Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado, Denver, CO.

Correspondence to: Andrew Churg, MD, Department of Pathology, University of British Columbia, Canada V6T 2B5; e-mail: achurg@interchange.ubc.ca



Chest. 2006;129(5):1117-1118. doi:10.1378/chest.129.5.1117
Text Size: A A A
Published online

Extract

Usual interstitial pneumonia (UIP), the underlying histology of idiopathic pulmonary fibrosis (IPF), has a poor prognosis (median survival, 3 years), and to date there is no impressively effective therapy. Therefore, at least for prognosis, and in some cases for early transplant referral, it is important to confirm this diagnosis.

Expert radiologists and clinicians can accomplish this in approximately 50% of cases of UIP with a high degree of specificity.1 When typical radiologic features are present and tissue acquisition is deemed unnecessary, most clinicians feel that the disease is already advanced. However, there are a number of patients without typical radiologic findings, and also younger subjects, in whom a histologic diagnosis is often necessary. In addition, a number of treatment trials are in motion for IPF and a tissue diagnosis is required for inclusion in these trials.

First Page Preview

View Large
First page PDF preview

Sign In to Access Full Content

MEMBER & INDIVIDUAL SUBSCRIBER

Want Access?

NEW TO CHEST?

Become a CHEST member and receive a FREE subscription as a benefit of membership.

Individuals can purchase this article on ScienceDirect.

Individuals can purchase a subscription to the journal.

Individuals can purchase a subscription to the journal or buy individual articles.

Learn more about membership or Purchase a Full Subscription.

INSTITUTIONAL ACCESS

Institutional access is now available through ScienceDirect and can be purchased at myelsevier.com.

Sign In to Access Full Content

MEMBER & INDIVIDUAL SUBSCRIBER

Want Access?

NEW TO CHEST?

Become a CHEST member and receive a FREE subscription as a benefit of membership.

Individuals can purchase this article on ScienceDirect.

Individuals can purchase a subscription to the journal.

Individuals can purchase a subscription to the journal or buy individual articles.

Learn more about membership or Purchase a Full Subscription.

INSTITUTIONAL ACCESS

Institutional access is now available through ScienceDirect and can be purchased at myelsevier.com.

Figures

Tables

References

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

MEMBER & INDIVIDUAL SUBSCRIBER

Want Access?

NEW TO CHEST?

Become a CHEST member and receive a FREE subscription as a benefit of membership.

Individuals can purchase this article on ScienceDirect.

Individuals can purchase a subscription to the journal.

Individuals can purchase a subscription to the journal or buy individual articles.

Learn more about membership or Purchase a Full Subscription.

INSTITUTIONAL ACCESS

Institutional access is now available through ScienceDirect and can be purchased at myelsevier.com.

Related Content

Customize your page view by dragging & repositioning the boxes below.

CHEST Journal Articles
PubMed Articles
  • CHEST Journal
    Print ISSN: 0012-3692
    Online ISSN: 1931-3543