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Early Goal-Directed Therapy in Severe Sepsis and Septic Shock : Converting Science to Reality

Emanuel P. Rivers, MD, MPH, FCCP
Author and Funding Information

Affiliations: Detroit, MI
 ,  Dr. Rivers is Senior Staff Attending, Departments of Emergency Medicine and Surgery, Director of Research, Department of Emergency Medicine, Henry Ford Hospital, Wayne State University.

Correspondence to: Emanuel P. Rivers, MD, MPH, FCCP, Henry Ford Hospital, CFP-270, 2799 W Grand Blvd, Detroit, MI 48202-2608; e-mail: erivers1@hfhs.org



Chest. 2006;129(2):217-218. doi:10.1378/chest.129.2.217
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Dr. Stephen Trzeciak and colleagues1 should be congratulated on their publication in CHEST (see page 225). November 8, 2005 was the fourth anniversary of the original publication of our article2 on early goal-directed therapy (EGDT) in severe sepsis and septic shock. In replicating this study, Trzeciak et al1 not only were the first to publish similar results to the original study; more importantly, they answered the frequently posed question of whether these results can be translated into reality.

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