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Editorials |

Treatment Strategy for Asthma: One for All and All for One?

Krishnan Parameswaran, MD, PhD, FCCP
Author and Funding Information

Affiliations: Hamilton, ON, Canada
 ,  Dr. Parameswaran is Assistant Professor of Medicine, McMaster University, Firestone Institute for Respiratory Health, St. Joseph’s Healthcare.

Correspondence to: Krishnan Parameswaran, MD, PhD, FCCP, McMaster University, Firestone Institute for Respiratory Health, St. Joseph’s Healthcare, Hamilton, ON, L8N 4A6 Canada; e-mail: parames@mcmaster.ca



Chest. 2006;129(2):221-223. doi:10.1378/chest.129.2.221
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Treatment with inhaled antiinflammatory drugs and inhaled bronchodilators is the mainstay of treatment of asthma. Traditionally, inhaled corticosteroids have been considered to be the most effective treatment for the inflammatory component of asthma, and β2-agonists have been considered as the most effective bronchodilator. The demonstration that the combination of an inhaled corticosteroid with a long-acting β2-agonist, on average, improved measures of airflow better than higher doses of inhaled corticosteroids alone13 prompted national and international guidelines to recommend therapy with a combination of the two drugs when asthma is inadequately controlled with a moderate dose of inhaled corticosteroids.4

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