We appreciate very much the comments by Birring and Pavord on our article in CHEST (May 2005).1In our study, we described a condition characterized by dry cough and a lymphocytic bronchitis dominated by activated CD4+ cells. Apart from dry cough, all patients were, according to the inclusion criteria, otherwise asymptomatic and were not receiving regular treatment with drugs. This condition, which was characterized by dry cough as the only symptom, was found only in women, and it seemed to have commenced in connection with an airway infection that coincided with the menopause. Although we did not take specific diagnostic measures in order to prove the existence of hypothyreosis, diabetes mellitus, pernicious anemia, inflammatory bowel disease, Sjögren syndrome, or other autoimmune conditions, no patients had symptoms that led us into the suspicion of organ-specific autoimmune diseases. We agree that further immunopathologic studies are required for a more detailed identification of the condition. It is an intriguing thought that the described “dry cough condition” is mediated by autoimmune mechanisms and that infections during menopause may increase the inclination toward development of autoimmune disorders. In healthy menopausal women, there are indications on an increase in airway T-helper lymphocytes and a shift in the relation between T-helper and T-cytotoxic cells.2 It could be speculated that such changes in T-cell function by menopause may constitute the basis for an altered immune response to a common infection.