The new cover or “face” of the January, 2006 issue of CHEST heralds that changes have taken place in the editorial content and format of what will be published in the pages of the Journal as we begin a new era in its 71-year history. The cover was redesigned to reflect the changes that will occur. While the new design appears fresher and more modern, it has not lost the identity of its heritage. In this regard, while it is my goal, and that of the Associate Editors and new Editorial Board members, to improve the quality of research and scholarly works and educational offerings published in CHEST, and in advancing our field, we will not attempt to do so at the expense of publishing what our readers expect and need. CHEST is above all else a clinical journal, with a very important educational mission.