0
Clinical Investigations: CARDIOLOGY |

Correlation of Left Atrial Size With P-Wave Duration in Interatrial Block*

Vignendra Ariyarajah, MD; Kristin Mercado, MD; Sirin Apiyasawat, MD; Puneet Puri, MD; David H. Spodick, MD
Author and Funding Information

*From the Massachusetts Veterans Epidemiology Research and Information Center, Veterans Affairs Boston Healthcare System, and Department of Medicine (Dr. Ariyarajah), Brigham and Women’s Hospital, Harvard Medical School, Boston; Division of Cardiology (Drs. Mercado and Apiyasawat), Department of Medicine (Dr. Puri), Saint Vincent Hospital, Worcester; and Division of Cardiovascular Medicine (Dr. Spodick), University of Massachusetts Medical School, Worcester, MA.

Correspondence to: Vignendra Ariyarajah, MD, Preventive Cardiology, MAVERIC, VA Boston Health Care System, 150 South Huntington Ave, Boston, MA 02130; e-mail: vignendra@hotmail.com



Chest. 2005;128(4):2615-2618. doi:10.1378/chest.128.4.2615
Text Size: A A A
Published online

Background: Interatrial block (IAB) [P-wave duration ≥ 110 ms] is associated with left atrial (LA) enlargement (LAE) and pathophysiologic derangements that result in atrial tachyarrhythmias, LA electromechanical dysfunction, and embolism. However, there has been no study addressing the direct correlation of P-wave duration in IAB and LAE.

Methods: One hundred eighty-one consecutive patients who were admitted to a tertiary care teaching hospital over 5 consecutive days were screened for past transthoracic echocardiogram evaluations and were then matched with ECGs done within 10 days of these echocardiographic investigations. ECGs were evaluated for presence of IAB, and patients were subsequently classified into two groups: control patients and patients with IAB. Patients were also matched for common comorbidities. Mean, SD of age, Pearson correlation coefficient (r), p values, and multivariate and linear regression analyses were analyzed for the investigated variables of LA size, left ventricular hypertrophy (LVH), posterior wall thickness, septal thickness, and P-wave duration.

Results: From the sample (n = 66; mean age ± SD, 71.3 ± 13.7; female gender, 48.5%), the mean LA size in the control group was 36.7 ± 4.01 mm and for the group of patients with IAB (n = 38) was 42.2 ± 7.25 mm (p = 0.004). Linear regression analysis revealed that P-wave duration was significantly correlated with LA size (p = 0.0002, r = 0.606).

Conclusions: Degree of conduction delay in IAB (P-wave duration) is an independent, direct correlate of LAE, and the regression equation (LA size [in millimeters] = 2.47 ± 0.29 × P-wave duration [in milliseconds]) could be used to estimate LAE.

Figures in this Article

Sign In to Access Full Content

MEMBER & INDIVIDUAL SUBSCRIBER

Want Access?

NEW TO CHEST?

Become a CHEST member and receive a FREE subscription as a benefit of membership.

Individuals can purchase this article on ScienceDirect.

Individuals can purchase a subscription to the journal.

Individuals can purchase a subscription to the journal or buy individual articles.

Learn more about membership or Purchase a Full Subscription.

INSTITUTIONAL ACCESS

Institutional access is now available through ScienceDirect and can be purchased at myelsevier.com.

Sign In to Access Full Content

MEMBER & INDIVIDUAL SUBSCRIBER

Want Access?

NEW TO CHEST?

Become a CHEST member and receive a FREE subscription as a benefit of membership.

Individuals can purchase this article on ScienceDirect.

Individuals can purchase a subscription to the journal.

Individuals can purchase a subscription to the journal or buy individual articles.

Learn more about membership or Purchase a Full Subscription.

INSTITUTIONAL ACCESS

Institutional access is now available through ScienceDirect and can be purchased at myelsevier.com.

Figures

Tables

References

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

MEMBER & INDIVIDUAL SUBSCRIBER

Want Access?

NEW TO CHEST?

Become a CHEST member and receive a FREE subscription as a benefit of membership.

Individuals can purchase this article on ScienceDirect.

Individuals can purchase a subscription to the journal.

Individuals can purchase a subscription to the journal or buy individual articles.

Learn more about membership or Purchase a Full Subscription.

INSTITUTIONAL ACCESS

Institutional access is now available through ScienceDirect and can be purchased at myelsevier.com.

Related Content

Customize your page view by dragging & repositioning the boxes below.

CHEST Journal Articles
PubMed Articles
  • CHEST Journal
    Print ISSN: 0012-3692
    Online ISSN: 1931-3543