In the absence of prior instrumentation, dura and bony structures of the skull base provide a tight barrier between the subarachnoid space and the adjacent air-containing cavities. Nonetheless, the cribriform plate has been implicated in the development of CSF leak, as its thin structure makes it vulnerable to the effects of positive pressure. In fact, congenital fistulas across the cribriform plate are thought to be the cause of spontaneous CSF leaks.8 While these defects may be congenital, they may also be acquired during prior surgery involving air-containing cavities or through presence of an erosive process involving the dura.8–9 Conceivably, nCPAP may unmask a subclinical defect/communication between subarachnoid space and the aerated spaces that are exposed to positive pressure such as nasal cavity, sinuses, and middle ear, and consequently cause CSF leak. While temporal relationship between the initiation of nCPAP and onset of rhinorrhea in patient 2 suggests such a causal relationship, this is difficult to postulate in patient 1. CT cisternogram results further supported this possibility in patient 2. Nevertheless, we believe the most interesting aspect of these cases is the nonspecificity of the clear rhinorrhea, which could have been easily attributed to nCPAP therapy and resulted in overlooking of the symptom and dismissal of the real cause, the CSF leak.